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'Prodigy' vs 'Progeny' What's the Difference Descendants refers to individuals who are born as a result the act of generation. It connotes the continuation of family as well as the handover of characteristics from guardian to child. The definition of progeny extends beyond biological offspring, including spiritual children, as well as even notions that are passed on from one generation to the next. Offspring inherit the legacy of their ancestors, creating them a link among past and upcoming.